Català Castellano
DEGREE CURRICULUM
NUTRIENT AND DRUG INTERACTION
Coordination:
TABERNER BONASTRE, PILAR
Academic year 2022-23
DEGREE CURRICULUM: NUTRIENT AND DRUG INTERACTION 2022-23

Subject's general information
Subject nameNUTRIENT AND DRUG INTERACTION
Code100639
Semester2nd Q(SEMESTER) CONTINUED EVALUATION
Typology
DegreeCourseCharacterModality
Bachelor's Degree in Human Nutrition and Dietetics3COMPULSORYAttendance-based
Course number of credits (ECTS)3
Type of activity, credits, and groups
Activity typePRAULATEORIA
Number of credits1.51.5
Number of groups21
CoordinationTABERNER BONASTRE, PILAR
DepartmentMEDICINE
Important information on data processingConsult this link for more information.
Teaching staffE-mail addressesCredits taught by teacherOffice and hour of attention
MARTINEZ CASTRO, BEATRIZbeatriz.martinez@udl.cat,5
NEVOT BLANC, MARIAmaria.nevot@udl.cat3
TABERNER BONASTRE, PILARpilar.taberner@udl.cat1
Subject's extra information

Drug-nutrient interactions are a problem of great importance in clinical practice, since they can alter the nutritional status of the individual or the pharmacological response. These interactions are difficult to detect and identify, and their importance will depend on the characteristics of the drug and the patient.

The topics to be dealt with in this subject are highly topical since drugs are increasingly more specific, and the population is older and uses a greater number of drugs and for longer periods of time. In addition, it must be taken into account that the consumption of functional foods, phytotherapy and food supplements is increasing, which in most cases are perceived as harmless by patients and, however, can give rise to important interactions. Likewise, we must also take into account the possible interactions of drugs with artificial nutritional support both at the hospital and home level.

Drug-nutrient interactions are bidirectional. On the one hand, the nutritional status of the individual can be altered and, on the other, the efficacy or safety of pharmacological treatment.

Therefore, it is necessary for the students of the Degree in Human Nutrition and Dietetics to be aware of the possible interactions, to try to avoid them or detect them in the event that they occur.

This subject requires knowledge of Pharmacology, and since it is the first time that the student of the Degree comes into contact with this subject, concepts of said discipline will be treated so that the student can achieve a better understanding of the subject.

Learning objectives

Students who pass this course should have achieved the following teaching objectives:

Competences
Subject contents

THEORETICAL CONTENT

Chapter

Description

Hours

Teacher

1

Introduction to Pharmacology

1

 

2

Pharmacokinetics (Absorption, distribution, metabolism and elimination of drugs) and pharmacodynamics

1

 

3

Pharmaceutical forms. Routes of administration

1

 

4

Adverse reactions. Pharmacovigilance

1

 

5

Pharmacological interactions: pharmacokinetics and pharmacodynamics

1

 

6

Pharmacokinetic and pharmacodynamic drug-food interactions

1

 

7

Drugs and electrolytes (sodium, magnesium, potassium)

1

 

8

Most prevalent pathological interactions: heart disease (hypertension, heart failure...), diabetes, dyslipidemia, Central Nervous System

1

 

9

Drug-food interactions in anorexia and obesity: androgens and anabolics. Estrogens and progestins. contraceptives

1

 

10

Drug-food interactions in special situations: pediatrics, pregnancy, lactation, geriatrics, AIDS, cancer and organ transplants

1

 

11

Interactions of drugs with additives, contaminants, tobacco and alcohol

1

 

12

Interactions of drugs with medicinal plants

1

 

13

Drug interactions with artificial nutrition

1

 

14

Effects of drugs on nutritional status

1

 

15

Effects of nutritional status on the effect of drugs

1

 

14 hours of seminars are scheduled, in 7 seminars of 2 hours each. Students are divided into groups. 

PRACTICAL CONTENT

Methodology

To achieve the objectives and acquire the assigned skills, the following activities are scheduled:

They are carried out with all students and are not compulsory. Their purpose is to provide an overview of the educational content related to the specific knowledge of the subject, highlighting those aspects that are related to the acquisition of skills. The transmission of information will be carried out through oral presentations and the support of presentations in pdf format (which the student will have at their disposal on the virtual campus). Classes may be face-to-face or virtual (through the virtual campus).

Seminars are scheduled in two groups and will be mandatory. These consist of carrying out complementary activities in order to delve into the aspects dealt with in the matter. The student must solve problems through personal and team work.

They will have the purpose of sharing the thematic contents, guiding learning, clarifying doubts and establishing a conceptual diagram. It is an activity that will be carried out at the request of the students after previously contacting the corresponding teacher by email.

Evaluation

Continuous evaluation will be carried out through 2 controls of the theoretical contents (multiple tests), which will account for 40% of the first part and 40% of the second. Each of the partials will be approved separately. The sum of the two will account for 80% of the final grade.

The final mark will be the sum of the different aspects evaluated:

Theoretical content

80% of the final grade

Practical contents

20% of the final grade

Multiple choice test

Controlled attendance and works

1st control: 40%

2on control: 40%

Seminars: 20 %

Bibliography

Farmacología básica y clínica / Velázquez; P. Lorenzo ... [et al.]. Panamericana; 2005

Versió paper: https://discovery.udl.cat/iii/encore/record/C__Rb1191262?lang=cat

 

Farmacología clínica y terapéutica médica 4ª ed. / colaboradores: A. Velasco Martín, A. Alsásua del Valle, A. Carvajal García-Pando. McGraw-Hill Interamericana. 2004

Versió electrònica:

https://discovery.udl.cat/iii/encore/record/C__Rb1330123?lang=cat

 

Introducción a las Interacciones Farmacológicas / Coordinado por Lourdes Girona Brumós. Sociedad Española de Farmacia Hospitalaria. 2013

Versió electrònica:  https://discovery.udl.cat/iii/encore/record/C__Rb1330123?lang=cat

 

Aguilar Ros A. Biofarmacia y farmacocinética : ejercicios y problemas resueltos. Elsevier; 2008

Versió paper

 

Alvariza, Silvana ;Bentancur, Camilo. Guía de Farmacocinética. Universidad de la República   2010

Versió electrònica (directe plataforma Proquest):

https://ebookcentral.proquest.com/lib/udl/reader.action?docID=5213845

 

Baños Díez J-E, Farré Albaladejo M. Principios de farmacología clínica : bases científicas de la utilización de medicamentos. Masson; 2002

Versió paper: https://discovery.udl.cat/iii/encore/record/C__Rb1152677?lang=cat

 

Balada Nicolau, Ferran ;Márquez Vega, Cristina. Farmacología y endocrinología del comportamiento. Editorial UOC   2012

Versió electrònica (directe plataforma Proquest):

https://ebookcentral.proquest.com/lib/udl/reader.action?docID=3207937

 

Ballesteros Pomar M.D. Interacción entre dieta y fármacos. Ediciones Díaz de Santos   2010

Versió electrònica (directe plataforma Proquest):

https://ebookcentral.proquest.com/lib/udl/reader.action?docID=3206145

 

Birkett D.J. Farmacocinética fácil: revisado. McGraw-Hill Interamericana. 2005

Versió electrònica (directe plataforma Proquest):

https://ebookcentral.proquest.com/lib/udl/reader.action?docID=3192791

 

Blade Font A, Ordorica Vargas J.G. Apuntes sobre mecanismos de acción de fármacos: farmacología. Instituto Politécnico Nacional  Instituto Politécnico Nacional. 2010

Versión electrònica (directo plataforma Proquest): https://ebookcentral.proquest.com/lib/udl/reader.action?docID=3187661

 

Brunton LL, Chabner B, Knollmann BC. Goodman & Gilman las bases farmacológicas de la terapéutica. McGrawHill; 2012

Versió paper: https://discovery.udl.cat/iii/encore/record/C__Rb1316847?lang=cat

 

Claramunt Vallespí R.M., Cabildo Miranda M.P. Fármacos y medicamentos. UNED - Universidad Nacional de Educación a Distancia. 2015

Versió electrònica (directe plataforma Proquest):

https://ebookcentral.proquest.com/lib/udl/reader.action?docID=3430560

 

Flórez J, Armijo JA, Mediavilla A. Farmacologia humana. Elsevier Masson,; 2014

Versió paper: https://discovery.udl.cat/iii/encore/record/C__Rb1315854?lang=cat

Versió electrònica: https://discovery.udl.cat/iii/encore/record/C__Rb1351447?lang=cat

 

Frankel, Eric H. ;Wolfe, Jonathan J. Handbook of Food-Drug Interactions. CRC Press LLC   2003

Versió electrònica (directe plataforma Proquest):

https://ebookcentral.proquest.com/lib/udl/reader.action?docID=2010200

 

Jaramillo González, Francisco. Toxicología básica. Universidad Autónoma de Aguascalientes   2006

Versió electrònica (directe plataforma Proquest):

https://ebookcentral.proquest.com/lib/udl/reader.action?docID=3214714

 

Kalant H, Roschlau WHE, Sánchez Monsiváis RI. Principios de farmacología médica. Oxford; 2002

Versió paper: https://discovery.udl.cat/iii/encore/record/C__Rb1154500?lang=cat

 

Katzung, Bertram G. ;Masters, Susan B. Farmacología básica y clínica (11a. ed.). McGraw-Hill Interamericana   2010

Versió electrònica (directe plataforma Proquest):

https://ebookcentral.proquest.com/lib/udl/reader.action?docID=4385676

 

Lorenzo Fernández P de. Velázquez farmacología básica y clínica Editorial Médica Panamericana,; 2017

Versió paper: https://discovery.udl.cat/iii/encore/record/C__Rb1367655?lang=cat

 

Mestres Miralles C, Duran Hortolà M. Farmacología en Nutrición.  Editorial Médica Panamericana; 2011

Versió paper: https://discovery.udl.cat/iii/encore/record/C__Rb1346410?lang=cat

 

Page C. Lo esencial en farmacología. Elsevier, 2019

Versió paper: https://discovery.udl.cat/iii/encore/record/C__Rb1375927?lang=cat

 

Rang H, Dale M.           Farmacologia: Rang y Dale 8ª ed. Elsevier.2016

Versió paper: https://discovery.udl.cat/iii/encore/record/C__Rb1335926?lang=cat

 

Gil A. Tratado de nutrición. Editorial Médica panamericana. 2017

Versió paper: https://discovery.udl.cat/iii/encore/record/C__Rb1348999?lang=cat

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